Myoglobin/CK-MB/Troponin I Kit
Myoglobin, Creatine Kinase (CK-MB), and Troponin I are three of the most common cardiac markers. Myoglobin is a hemeprotein typically found in skeletal and cardiac muscles, responsible for transporting oxygen within muscle cells. Due to its small size, myoglobin levels rise rapidly (within two hours) following muscle injury, peak at 10 hours, and return to baseline within 24 to 36 hours. However, since this protein is not specific to cardiac muscle, results must be confirmed using other cardiac markers. Creatine Kinase (CK) is an enzyme that converts creatine to phosphocreatine (and vice versa) using adenosine triphosphate (ATP). CK is expressed in various human body tissues, particularly those with high ATP consumption. The level of CK-MB—which is specific to the heart—rises more slowly (within 3 to 12 hours), peaks between 9 and 30 hours, and remains elevated for a period before returning to baseline (within 48 to 72 hours). The differences in the timing of the rise in myoglobin, CK-MB, and Troponin I levels provide a broad and excellent window for diagnosing cardiac conditions.
Monitoring the levels of these proteins is also vital throughout the course of treatment.
Intended Use:
The Myoglobin / CK-MB / Troponin I test is an immunochromatographic assay for the qualitative detection of human cardiac markers (Myoglobin, CK-MB, and Troponin I) in human whole blood, serum, or plasma, aiding in the diagnosis of myocardial infarction (MI).
• Simultaneous and sensitive detection of 3 key cardiac markers.
• Confirmed lack of cross-reactivity with skeletal Troponin I, Troponin T, CK-MM, CK-BB, and cardiac myosin.
For Myoglobin, CK-MB, and Troponin I:
Sensitivity: 99.9%
Specificity: 99.0%